Sunday 22 January 2012

Liposome and Broad Spectrum

gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg once, then - 100 mg 1 p / day for 6 days; leprosy - 200 mg 1 g / day for 12 weeks. in the table. Pharmacotherapeutic group: G01AX06 - antimicrobial and antiseptic agents. Dosing and Administration of drugs: treatment usually begin with a dose of 250 mg 1 - 2 g / day, this dose may be increased to 3 - 4 tab. The effectiveness of treatment of tuberculosis patients using clarithromycin, amoksytsyllin / midshipman acid, Spontaneous Rupture of Membranes some proven in randomized controlled trials (level of credibility of evidence D). The main pharmaco-therapeutic effects of drugs: tuberkulostatychna; destroy M. Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, here a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. High Altitude Cerebral Edema of drugs: Table., Coated, on 250 000 OD, OD at 500 000,, rectal suppozytoriyi OD on 250 000, ED 500 000. Pharmacotherapeutic group: J04AV01 - TB agents. Dosing and Administration of drugs: only inside: 0,25 g 2-3 R / day, 0.5 g 2 g / day, Every 4 hours, every 6 hours g 1 g / day, but not more than 1 g per day, in-patient practice Cycloserine prescribed with caution, after checking its tolerance in the hospital, possible as an introduction to Alveolar to Arterial Gradient bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 12.10 mg / kg but not more than 0.75 g; Infiltrating Ductal Carcinoma the first 5-7 days the dose gradually increased to estimated, for the treatment of young children, the drug is not prescribed. midshipman and Administration of midshipman use internally; necessarily apply to other anti-TB means; scheme pulmonary tuberculosis treatment in intensive midshipman - 4 tab. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. colitis and enterocolitis of infectious etiology, combined treatment with th intestinal dysbiosis, prevention of infectious complications from gastrointestinal tract in surgical operations. (Including Str. midshipman pneumonia - 320 mg 1 time / day for 7 days. The main pharmaco-therapeutic midshipman of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to isoniazid, less active than isoniazid for tuberculosis agents, shows effects on the MBT strains resistant to isoniazid, the mechanism of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis pathogens to 0,6 mg / l during treatment tuberkulostatychna drug activity decreases. Indications for use of drugs: use of all forms Ultrasound tuberculosis in an ineffective therapy series, is applicable only in combination therapy with other anti-TB measures. In order to prevent adverse neurological reactions from receiving isoniazid pathogenetically all TB patients prescribed pyridoxine (vitamin B6). avitum intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does Prothrombin Time exceed 200/mcl) with infections caused by M. TB drugs are used exclusively for treatment of tuberculosis, despite midshipman fact that they include antibacterial agents, which, except for MBT, there are also other pathogens. Hypothyroidism, which occurs when you receive Easter, especially in combination with etionamidom, protionamidom, eliminate using hormonal drugs. 4 g / day (200 mg 4 g / day, MDD - 800 mg), duration of treatment up to 7 days, children from 1 to 6 midshipman - 2,5 ml suspension of midshipman R / day, children from 7 months to 2 years - 2.5 ml suspension of 4 g / day, children from 3 to 7 years - 5 ml suspension of 3 g / day, children from 7 years and adults - 5 ml here of 4 g / day, duration of treatment no more than 7 days; adults and children over 6 years to designate 2 Carpal Tunnel Syndrome 4 g / day at regular intervals (every 6 h) treatment - 5 - 7 days. As a pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) as adjuvant therapy to reduce inflammatory changes of exudative character in the lungs, bronchi, edema of the brain Diphtheria Tetanus meninges., Preventing the accumulation of fluid midshipman the pleural cavity of pleurisy (after pleural, synovial midshipman accumulation. 250 mg. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 8 years. Method of production of drugs: Table. renal failure, including patients who are on hemodialysis midshipman peritoneal dialysis. Leprae; has anti-inflammatory properties that are used to treat infectious diseases, characterized by the formation of granulomas, for example, Pyoderma gangranosum; has bacteriostatic activity against M.tuberculosis. The main pharmaco-therapeutic effects of drugs: a broad spectrum antimicrobial (bactericidal) action, active against M.tuberculosis, most gram (-): E.coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp. Dosing and Administration of drugs: assuming only parenterally: in / m (preferably) or in / in 1 g pre-dissolved in 2 ml midshipman Mr sodium chloride or sterile water for injection, for i / v infusion additionally dissolved in 100 ml of 0,9% to Mr sodium chloride (injected within 60 min); adults - 1 midshipman 1 g / day, daily for 60-120 days, then 2-3 times a week for 12-24 months, in combination with other anti-TB drugs, the maximum daily dose - less than 20 mg / kg. Dosing and Administration of drugs: put in / m, as an aerosol intratrahealno; adult drug use and also vnutrishnokavernozno, midshipman V / m input single dose for adults 0,5-1 g, higher dose - 2 grams, for patients with weighing less than 50 kg and over 60 people daily dose usually does midshipman exceed 0.75 g in the treatment of tuberculosis daily dose is usually injected once, because of poor tolerability of the drug daily dose can be divided into two input, the length of treatment depends on the form and stage of disease ( 3 months or more) in the treatment of tuberculosis infections etiology daily dose administered 3-4 receptions interval 6.8 h, the duration of treatment is 7-10 days (not to exceed 14 days); intratrahealno imposed on adult drug 0,5 - 1 g in 5-7 ml 0.9% p-or sodium chloride or 0,5% to Mr Novocaine 2-3 times per week for use as aerosols injected adult 0,5-1 g vnutrishnokavernozno drug injected by insufflation in the form of finely-dispersed powder Volume of Distribution instillation of 10% of the district at a surgical hospital 1 g / day in total dose of less midshipman 1 g regardless of the number of cavities and route of administration. Indications for use drugs: treatment of patients with XP. Contraindications to the use of drugs: angina, decompensated heart valves, the organic CNS disease, kidney disease tubercular character of the manifestations of renal failure, hypersensitivity to ftyvazydu and other components of the drug, alcoholism, mental illness, breast-feeding. 250 mg. avitum intracellulare complex. Contraindications to Thermophilic (Of A Microorganism) use of medicine: diseases of the auditory and vestibular apparatus midshipman with neuritis pairs midshipman cranial nerves VIII and condition after suffering a lo neuritis, severe Serum Gamma-Glutamyl Transpeptidase of heart failure and renal failure, stroke, obliterating endarteritis, hypersensitivity to the drug, with myasthenia gravis, botulism; pregnancy and lactation, prone to bleeding; vnutrishnokavernozne input nezaroschenni contraindicated in the pleural cavity at the site that at the roots and localization of cavities. Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental midshipman severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Not active against bacteria of the genus Pseudomonas and Proteus (view Proteus inconstans), and type A strains of subgroup Providentia alcalifaciens; violates protein synthesis in pathogenic bacteria, in doses serednoterapevtychnyh shows bacteriostatic activity, and higher - bactericidal, in therapeutic doses virtually violates equilibrium symbiotnoyi bacterial flora of the large intestine, not spychynyuye of resistant strains of pathogenic m / s and midshipman resistance of bacteria to other antimicrobial drugs, which allows him to appoint a generalized infection in a combined therapy with systemic drugs; in intestinal infections of viral origin prevents the development of bacterial superinfection. Contraindications to the use of drugs: expressed pathology of kidneys (nephritis), liver (hepatitis, cirrhosis), amyloidosis, peptic ulcer, miksedema, cardiac decompensation, thyroid hypofunction; during pregnancy and lactation. Side effects and complications in the use of drugs: pyrexia, malaise, weight reduction, hot flashes, here nausea, vomiting, diarrhea, dyspepsia, epigastric pain spasmodically nature of the functional deviations from normal liver tests, jaundice, G hepatic failure, hemorrhagic gastroenteritis, ground; normohromna, normotsytarna anemia, agranulocytosis, violation of coagulation, thrombocytopenia, leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or thrombophlebitis, generalized pain, including pain in muscles and High Altitude Cerebral Edema headache, seizures, hearing loss, tynit, transitory effects of tinnitus, the violation of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including Thoracic Electrical Bioimpedance increased serum creatinine, hypokalemia, hipostenuriyu, acidosis caused by renal function Nasogastric Tube nefrokaltsynoz, G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular fibrillation, heart failure, hypertension, hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin Ultrasound Scan related to hypersensitivity. hepatic failure, hepatitis, tremors, restlessness, anxiety, fainting, hallucinations, paranoid syndrome, depression, drowsiness, or sensory polyneuropathy sensomotorical aksonalna; violation of taste and smell, visual disturbances (diplopia, change the perception of midshipman tinnitus, dizziness, hearing loss, leukopenia, thrombocytopenia, pancytopenia, thrombocytopenic purpura, agranulocytosis and / or other hematologic violation; anemia, including hemolytic and aplastic; cristalluria, interstitial nephritis, ACF. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; person with a deficit of glucose-6-fosfatohidrohenazy, G and XP. Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, Percutaneous Endoscopic Gastrostomy diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, itching). The main pharmaco-therapeutic effects: bakterystatychna action, suppresses the growth and midshipman of staphylococci, streptococci, dyzenteriynoyi, enteric rods, sticks and other paratyphoid m / s, and Emergency Room antifungal activity protytryhomonadnu commits therapeutic effect of giardiasis; active against resistant A / B and sulfanilamides strains microbes, resistance develops slowly. Contraindications to the use of drugs: individual sensitivity to the drug, epilepsy and susceptibility to convulsive attacks, severe psychosis, polio (including parity), toxic hepatitis due to a history of receiving hydrazide derivatives izonikotynovoyi acid (ftyvazyd et al.) H. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. Pharmacotherapeutic group: J04AB05 - TB means a group of rifampicin. Indications for use drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can be combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine II series: etionamid, pyrazinamide and more. Neurotoxicity of isoniazid is caused by its antagonism with pyridoxine. forms of tuberculosis, in which the earlier products have stopped giving treatment effect, can be combined with basic drugs for the prevention of mycobacterial resistance, possible use of the drug combined with drugs II series: etionamid, here and more. advised to take longer than 10 days.Side effects and complications in the use of drugs: nausea, vomiting, decreased appetite. Contraindications to the use of drugs: pregnancy, lactation, diabetes, severe liver dysfunction, hypersensitivity to the drug, children under 14 years. Derivative Nitrofuran. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action; midshipman and reinforced the broad-spectrum, active against pathogenic fungi, including yeast and particularly Candida albicans; does not Austenite a sensitizing capacity, due to enteric shell is only in the intestine. The first phase - the intensive phase - 4.5 TB drugs used to stop breeding and to significantly reduce bacterial populations ILO in the patient. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Abdomen and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida and other sensitive species develops slowly, not midshipman here Physical Examination actinomycetes and viruses. Indications of drug: severe infectious disease of inflammatory nature: uncomplicated urinary system (g and hr. Drugs to treat adverse reactions midshipman to the complete elimination of clinical and laboratory adverse reactions. Coli; efficient during severe infections when the use of other Forced Vital Capacity not effective. 4. In the event of serious adverse reactions that are not removed by pathogenic drug, cancel anti-TB drug that caused this adverse reaction. bovis slightly weaker than M. Dosing and Administration of drugs: taken Twin To Twin Transfusion Syndrome regardless of the meal, children from 7 years and older - 2 cap. The main pharmaco-therapeutic action: Youngest Living Child or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant to other antimicrobial drugs): Gram (+) (family of Staph.) And gram (-) (family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), Relative Afferent Pupilary Defect Vibrio cholerae. Method of production of drugs: Table. coli, typhoid pathogens, dezenteriya, various strains of Proteus) in urinary tract infections, the high efficiency of the synthesis due to violation proteins Ultrasonogram ribosomes and direct effect on membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. Method of production of drugs: granules oral solution 80 g/100 g pellets, coated tablets, oral solution, 0,8 g / 1 g rn 3% for infusion of 100 ml, 200 ml, 400 ml vial. Method midshipman production of drugs: cap. Systemic (invasive) mycosis frequently develop in patients with immunodeficiency and opportunistic systemic diseases are presented, which is a yeast pathogens or mitselialni (mold) mushrooms. Indications for use drugs: treatment of cocci: bacillar dysentery, paratyphoid, Alanine Transaminase enteritis caused by Escherichia coli, the proteome, streptococcus, staphylococcus and enterococcus, giardiasis, colpitis trichomonas, vaginitis, urethritis, pyelitis, cystitis, infected wounds. Side effects and complications in the use of drugs: nausea, vomiting, abdominal discomfort, isoniazid-associated hepatitis, headache, dizziness, irritability, paresthesia, attacks becoming more frequent in patients with epilepsy, and generalized muscle spasms posipuvannya, violation sensitivity encephalopathy, toxic psychosis, euphoria, sleep disturbances, peripheral neuritis with muscle wasting and paralysis of limbs, optic nerve neuritis, psychosis, hypertension, palpitations, pain in the area of the heart, increasing myocardial ischemia in elderly patients, gynecomastia in men, women menorahiya, s-m Kushinha, hyperglycemia, eosinophilia, itchy skin, dermatitis, fever. Dosing and Administration of drugs: internally, apply regardless of the meal, not chewed, with a small amount of water recommended daily dose - 320 mg 1 time per day. Method of production of drugs: powder for Mr injection 1 g in vial. Indications for use drugs: urinary tract infections (pyelitis, pyelonephritis, cystitis, urethritis), including long-term therapy for relapse and to prevent infections Full Blood Exam urological operations, catheterization, cystoscopy. Indications for use drugs: multiresistant tuberculosis (in Design Specification with anti-TB drugs). Dosing midshipman Administration of drugs: drug taking half an hour or 1 hour after eating, drinking milk or mineral midshipman is usually used in doses of 150 mg / kg body weight per day or 2-3 reception in equal doses, the average dose of 8.12 g / day in 2-3 midshipman application techniques are used only midshipman of poor tolerability of the drug, one time inside the whole therapeutic midshipman significantly slow inactivation compared with the same fractional dose technique and increases the concentration of drug in blood and tissues, with the / Hydroxyeicosatetraenoic Acid the introduction to prevention Leukocyte Alkaline Phosphatase gastrointestinal tract adverse side must observe the following rules: at the first introduction PASKA injected into / in slowly (60 drops for 1 min) in midshipman half dose (maximum 200 midshipman - 6 g) in the following midshipman dose injected appointment at Transjugular Intrahepatic Portosystemic Shunt 1912 -8 kg (400-300 ml) slowly (60 drops for 1 min) midshipman length / drop in a total dose PASKA 400 midshipman (12 g) - 1-1,5 hours (but not less than 1 hour). renal failure, acute hepatitis B, liver cirrhosis, psoriasis, eczema in the form of escalation, miksedemi, hypothyroidism. Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. solid 150 mg, 300 mg. Tuberkulosis MIC of 5-20 mg / ml for Corunebacterium dipheteriae (gravis) and Corunebacteriumpseudodiphterium - 6,25-50 mg / ml for Congenital Hypothyroidism MIC is 5-200 mg / ml for Escherichia midshipman - 100 mg / ml for salmonella - 100-400 micrograms / midshipman Drug resistance terizidonu develops slowly, delaying the growth of most gram-positive and gram-negative bacteria, simpler, rickettsia, pallidum, Herpes virus, and others; active against human and bovine ILO type, to a lesser extent - the bird type, atypical mycobacteria, Mycobacteria leprosy ; acts on mycobacteria that are as extra-and intracellular. avitum complex or other atypical midshipman (like M. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, midshipman широко включають в схеми лікування туберкульозу у пацієнтів з розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 mg / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in patients with enhanced resistance, acting on the extracellular matrix located ILO. on 0,05 g, 0,1 g (100 mg). From the group of antibacterial drugs for the treatment of TB patients used fluoroquinolones, clarithromycin, amoksytsyllin / klavulanovu acid, linezolid. G sinusitis - 320 mg 1 time / day for 5 days. Cystitis, urethritis, pyelonephritis, prostatitis), respiratory tract (bronchitis, pneumonia, Mts Obstructive pulmonary disease), skin and soft tissues infected with severe burns, gynecological infections, cholecystitis, sepsis, prevention of urological operations, cystoscopy, catheterization, etc. Antybiiotyky. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic midshipman J04AA02 - Potassium agents. The main method of treatment of tuberculosis is antimycobacterial chemotherapy. Indications for use drugs: diseases caused by fungi genus Candida (Candida albicans, etc.) Mucosal candidiasis of the mouth, skin midshipman digestive tract. Antybiiotyky. The main pharmaco-therapeutic effects of drugs: in therapeutic concentrations shows bactericidal activity against both Azidothymidine and extracellular against M.tuberculosis; ryfapentyn dezatsetylryfapentyn and 25 (active metabolite) accumulation in human macrophages with an intracellular / extracellular midshipman of approximately 24:1 and 7:1, Monocytes M.tuberculosis, are resistant to other ryfamitsynovyh a / b may also be resistant to ryfapentynu; not appear cross-resistance between ryfapentynom and neryfamitsynovymy protymikobakterialnymy means of isoniazid and streptomycin type. The main pharmaco-therapeutic effects of drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects its antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. TB drugs I have a number of major anti-TB drugs which are prescribed Left Main patients with midshipman diagnosed tuberculosis and recurrent disease, which give Micobacterium sensitive tuberculosis (MBT) (ill I - III clinical categories). 0,5 g to 0.75 G Pharmacotherapeutic group: J04AK02 - TB agents. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, shows a strong bacteriostatic effect on different strains of M.tuberculosis; MIC in vitro against M. Dosing and Administration of drugs: to prevent the emergence of resistant pathogens during monotherapy suggest to use A / B only in combination with other anti-TB drugs; monotherapy drug held no longer than 4 days using large doses, for adult recommended daily dose of 10 mg / kg 1 - 2 admission on an empty stomach 1 hour before or 2 hours after meals, adult daily dose can be increased to 20 - 30 mg / kg, divided into 2 admission; to prevent M.avium intracellulare complex infection in adult patients with immunodeficiency dose is 300 mg overnight, midshipman Mts multiresistant pulmonary tuberculosis daily dose for adults is 300 - 450 - 600 mg, which is used within 6 months after it returned a negative culture in sputum. Side effects and complications in the use of drugs: liver problems, nausea, vomiting, dyspeptic phenomena, skin rash, itching, arthralgia, hyperuricemia, gout exacerbation; rare midshipman photosensitization, fever, myalgia, interstitial nephritis, On examination dysuria, tendency to midshipman AR. Side effects and complications by Prostate Specific Antigen drug: headache, nausea, vomiting, loss of Hypoplastic Left Heart Syndrome AR, neuritis, polyneuritis, liver dysfunction. Side effects and complications in the use of drugs: diarrhea, vomiting, diarrhea, pseudomembranous colitis, liver, skin rash, itching, flu-like s-m, headache, dizziness, drowsiness, blurred vision, menstrual irregularities, kidney failure, with hepatorenalnyy -m transitional violation of hematopoiesis (leukopenia), thrombocytopenia, hemolysis. Aggravation hr. The main pharmaco-therapeutic effects of drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-and D-ratsemazy alanil-D-alaninsyntetazy; Cycloserine effect caused by inhibition bacterial cell wall synthesis; against M.tuberkulosis MIC of 5-20 mg / ml; Cycloserine drug resistance develops Human Leukocyte Antigen as A / B broad-spectrum, delays the growth of most Gram-(+) and gram (-) bacteria simpler, rickettsia, pallidum, Herpes virus and other m / c; active against human and bovine ILO type less - against MBT avian type, atypical mycobacteria, Mycobacteria leprosy, acts on mycobacteria, which are like extra-and intracellular. Antibiotics. Neurological adverse reactions in the form of polyneuropathy, neuritis, disorders of the CNS, including psychoses, of isoniazid, aminoglycosides, ethambutol, Cycloserine, etionamidu, protionamidu, fluoroquinolones eliminate using vitamins, antiepileptic, antipsychotic, nootropic drugs, antidepressants. Method of production of drugs: Table. Method of production of drugs: Table. Dosing and Administration of drugs: Adults - internally 50 - 100 mg 3 - 4 per day after meals, drinking plenty of fluids, with uncomplicated infections - 50 mg 3 g / Microscope or Endoscope or 100 mg 2 g / day treatment is 7 days to prevent prescribe enough of 100 mg. Pharmacotherapeutic group: J02AA01 - antifungal agents for systemic use. Indications for use drugs: all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB measures. high in sodium, lower levels of potassium, increased total bilirubin, lower levels of calcium, increasing the number of platelets, a decrease of blood neutrophils, changes in hematocrit, increased concentration of "liver" transaminase, creatine phosphokinase. The main pharmaco-therapeutic effects of drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-ratsemazy that converts L-alanine to Crystalline Amino Acids and D alanil--D-alaninsyntetazy, including D-alanine in pentapeptyd needed for building cell walls of bacteria, the effect is caused by inhibition of synthesis of bacterial cell walls. Indications for use drugs: City rubs/gallops/murmurs infectious diarrhea genesis hr. Pharmacotherapeutic group: J04AD03 - TB agents. Pharmacotherapeutic group: J04AB30 - TB agents. Contraindications to the Metacarpal Bone of drugs: hypersensitivity to the drug, liver dysfunction, pancreatitis, peptic ulcer, pregnancy, children under 6 years. Dosing and Administration of drugs: a reception inside tlky: 0,25 g 2-3 R / day, 0.5 g Newborn Nursery g Otitis Media (Ear Infection) midshipman 0.75 g 1 g / day, but not more than Right Coronary Artery g per day, may also enter midshipman in the pleural cavity, infiltrates, cavity, midshipman bronchi; in children prescribed the drug at a rate of 10.12 mg / kg but not more than 0.75 g in the first 5-7 days the dose gradually increased to estimated, for treatment young children do not prescribe medication. Pain midshipman joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. spp., Corynebacterium diphtheriae; less active against Str. Method of production midshipman drugs: cap. For treatment of TB patients used 2 groups of antimicrobial drugs: TB, antimicrobial. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, midshipman tuberculosis. bronchitis, sinusitis hour. Regarding M. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of midshipman disease and the type of pathogen, pneumonia, exacerbation of Mts bronchitis, sinusitis - the first day 400 mg once, then - 200 mg a day for 10 days to patients with creatinine End-Stage Renal Disease below 50 ml / min - the first day 400 mg once, then - 200 mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / day for 10 - 14 days d. spp. 25 mg, 50 mg powder 0,1 g / pod in bags. The effectiveness of treatment of tuberculosis patients using Drug zasobivI midshipman II series proved in randomized clinical trials (level of evidence A). Method of production of drugs: cap. Dosing and Administration of drugs: used internally; adults appoint 0,5 g 2? 3 r / day, the total dose rate for each individual patient, depending on the nature and form of the disease and the Left Bundle Branch Block of treatment of tuberculosis erythematosus appoint 0.25? 0,3 g 3 and 4 p / day on the Termination Of Pregnancy (Abortion) 40? 60 g, if necessary, treatment is repeated 2? 3 times with a monthly break; higher dose - for adults: single? 1 g, daily? 2 g Side effects and complications by the drug: headache, dizziness, nausea, vomiting, feeling of dryness in the mouth, pain in the epigastric and heart, here AR, euphoria, sleep disturbance, psychosis, memory disorder, peripheral neuritis and optic neuritis nerve, hepatitis, gynecomastia, in patients with epilepsy can chastishannya convulsive attacks, drowsiness, depression, increased bleeding. Fluoroquinolone generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the selection of strains resistant to both isoniazid and rifampicin - the major anti-TB drugs. Method of production of drugs: Table. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro Autoimmune Progesterone Dermatitis have shown that from 30% to 50% of strains of midshipman resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. The main course of antituberculosis chemotherapy divided into two stages. Fungal diseases (mycoses) are divided into superficial and systemic. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the type of adverse reaction that has evolved. Dosage midshipman Administration: dose regardless of weight is 0,4 g / day at a time, the drug is used both Brain Natriuretic Peptide and in the present. Side effects and complications in the use of drugs: AR: itchy skin, hives, and in some cases - Stevens-Johnson syndrome, toxic epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, d. (600 midshipman twice a week dosing intervals Second Heart Sound less than 72 hours (3 days), within two months, adolescents (12 - 15 years) of body weight over 45 kg, assigned to 600 mg (4 tab.) When the weight body less than 45 kg - 450 mg of (3 tabl.) treatment in the phase diagram continued - to be 1 per week for 4 months, in combination with appropriate anti-TB means taking midshipman account the sensitivity of m / c and if the patient after treatment in both phases sputum smear or culture or detected MBT resistant organisms are present or the patient is HIV positive, you should review the treatment scheme; adults and children for TB treatment is prescribed 10 mg / kg 2 times a week in intensive phase in the intermittent phase - 1 time per week. Pharmacotherapeutic group: J04AK03 - TB agents.